Separation of conformational isomers of bouvardin by high-pressure liquid chromatography

Joseph J. Hoffmann; Sterling J. Torrance; Jack R. Cole

doi:10.1093/chromsci/17.5.287

Separation of conformational isomers of bouvardin by high-pressure liquid chromatography

Joseph J. Hoffmann, Sterling J. Torrance, Jack R. Cole

Pharmacy Practice and Science

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10 Scopus citations

Abstract

Bouvardin, a bicyclic hexapeptide, was found to exhibit a solvent-dependent conformational distribution. HPLC was utilized to separate the two different conformers whose distribution ratio was dependent on the solvent of injection.

Original language	English (US)
Pages (from-to)	287-288
Number of pages	2
Journal	Journal of Chromatographic Science
Volume	17
Issue number	5
DOIs	https://doi.org/10.1093/chromsci/17.5.287
State	Published - May 1979

ASJC Scopus subject areas

Analytical Chemistry

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10.1093/chromsci/17.5.287

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title = "Separation of conformational isomers of bouvardin by high-pressure liquid chromatography",

abstract = "Bouvardin, a bicyclic hexapeptide, was found to exhibit a solvent-dependent conformational distribution. HPLC was utilized to separate the two different conformers whose distribution ratio was dependent on the solvent of injection.",

author = "Hoffmann, \{Joseph J.\} and Torrance, \{Sterling J.\} and Cole, \{Jack R.\}",

year = "1979",

month = may,

doi = "10.1093/chromsci/17.5.287",

language = "English (US)",

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pages = "287--288",

journal = "Journal of Chromatographic Science",

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T1 - Separation of conformational isomers of bouvardin by high-pressure liquid chromatography

AU - Hoffmann, Joseph J.

AU - Torrance, Sterling J.

AU - Cole, Jack R.

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N2 - Bouvardin, a bicyclic hexapeptide, was found to exhibit a solvent-dependent conformational distribution. HPLC was utilized to separate the two different conformers whose distribution ratio was dependent on the solvent of injection.

AB - Bouvardin, a bicyclic hexapeptide, was found to exhibit a solvent-dependent conformational distribution. HPLC was utilized to separate the two different conformers whose distribution ratio was dependent on the solvent of injection.

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U2 - 10.1093/chromsci/17.5.287

DO - 10.1093/chromsci/17.5.287

M3 - Article

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AN - SCOPUS:0018375506

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JO - Journal of Chromatographic Science

JF - Journal of Chromatographic Science

IS - 5

ER -

Separation of conformational isomers of bouvardin by high-pressure liquid chromatography

Abstract

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