DNA damage activates a set of proteins whose job is to delay the cell cycle until the damage is repaired. This process was thought to involve the detection of damage by sensor proteins, which transmit a signal to a key protein kinase and thence to downstream targets. Unexpectedly, damage can also activate the kinase directly.
|Original language||English (US)|
|Journal||Nature Cell Biology|
|State||Published - Nov 1999|
ASJC Scopus subject areas
- Cell Biology