Selective debenzylation of aromatic benzyl ethers by silica-supported sodium hydrogen sulfate

Linna Zhou, Wenjing Wang, Li Zuo, Shanyan Yao, Wei Wang, Wenhu Duan

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

A new debenzylation of aromatic benzyl ethers by silica-supported sodium hydrogen sulfate is described. The process proceeds selectively and efficiently in good to excellent yields without affecting sensitive functional groups such as nitro, COOMe, aldehyde, ketone, and tosyl.

Original languageEnglish (US)
Pages (from-to)4876-4878
Number of pages3
JournalTetrahedron Letters
Volume49
Issue number33
DOIs
StatePublished - Aug 11 2008
Externally publishedYes

Keywords

  • Aromatic benzyl ethers
  • Debenzylation
  • Silica-supported
  • Sodium hydrogen sulfate

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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