Secondary syphilitic uveitis

Michael Wellington Belin, Aldona L. Baltch, Peter B. Hay

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


A patient with secondary syphilis had positive serum and cerebrospinal fluid findings. Fluorescent-antibody darkfield testing demonstrated spirochetes (Treponema pallidum) in the aqueous. There were clinical signs of secondary syphilis, including palmar skin lesions and frontal balding, and bilateral nasal altitudinal visual field loss. The discrete, waxy, yellow-white retinal lesions became increasingly pigmented and later migrated anteriorly into the vitreous chamber. The patient was treated with large amounts of penicillin (total dosage, 440 million units) and probenecid. Visual acuity improved to R.E.: 6 9 ( 20 30) and L.E.: 6 12 ( 20 40) and the inflammatory reaction disappeared. A second aqueous tap eight weeks after therapy ended showed no spirochetes by fluorescent-antibody testing.

Original languageEnglish (US)
Pages (from-to)210-214
Number of pages5
JournalAmerican Journal of Ophthalmology
Issue number2
StatePublished - Aug 1981

ASJC Scopus subject areas

  • Ophthalmology


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