TY - JOUR
T1 - Secondary syphilitic uveitis
AU - Belin, Michael Wellington
AU - Baltch, Aldona L.
AU - Hay, Peter B.
N1 - Funding Information:
From the Departments of Ophthalmology (Dr. Belin) and Medicine (Dr. Baltch), Division of Infectious Diseases, Veterans Administration Medical Center, the Departments of Ophthalmology (Dr. Belin) and Medicine (Dr. Baltch), Albany Medical College, and the Veterans Administration Medical Center (Mr. Hay), Albany, New York. This study was supported in part by Training Grant EY07037 from the National Eye Institute (Dr. Belin) and by grants from the Veterans Administration (Drs. Belin and Baltch and Mr. Hay) and Research to Prevent Blindness, Inc. (Dr. Belin). Reprint requests to Michael W. Belin, M.D., Department of Ophthalmology, Albany Medical College, New Scotland Ave., Albany, NY 12208.
PY - 1981/8
Y1 - 1981/8
N2 - A patient with secondary syphilis had positive serum and cerebrospinal fluid findings. Fluorescent-antibody darkfield testing demonstrated spirochetes (Treponema pallidum) in the aqueous. There were clinical signs of secondary syphilis, including palmar skin lesions and frontal balding, and bilateral nasal altitudinal visual field loss. The discrete, waxy, yellow-white retinal lesions became increasingly pigmented and later migrated anteriorly into the vitreous chamber. The patient was treated with large amounts of penicillin (total dosage, 440 million units) and probenecid. Visual acuity improved to R.E.: 6 9 ( 20 30) and L.E.: 6 12 ( 20 40) and the inflammatory reaction disappeared. A second aqueous tap eight weeks after therapy ended showed no spirochetes by fluorescent-antibody testing.
AB - A patient with secondary syphilis had positive serum and cerebrospinal fluid findings. Fluorescent-antibody darkfield testing demonstrated spirochetes (Treponema pallidum) in the aqueous. There were clinical signs of secondary syphilis, including palmar skin lesions and frontal balding, and bilateral nasal altitudinal visual field loss. The discrete, waxy, yellow-white retinal lesions became increasingly pigmented and later migrated anteriorly into the vitreous chamber. The patient was treated with large amounts of penicillin (total dosage, 440 million units) and probenecid. Visual acuity improved to R.E.: 6 9 ( 20 30) and L.E.: 6 12 ( 20 40) and the inflammatory reaction disappeared. A second aqueous tap eight weeks after therapy ended showed no spirochetes by fluorescent-antibody testing.
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U2 - 10.1016/0002-9394(81)90773-X
DO - 10.1016/0002-9394(81)90773-X
M3 - Article
C2 - 7023241
AN - SCOPUS:0019495229
SN - 0002-9394
VL - 92
SP - 210
EP - 214
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
IS - 2
ER -