TY - JOUR
T1 - Screening for Latent Tuberculosis Infection in Adults
T2 - US Preventive Services Task Force Recommendation Statement
AU - Mangione, Carol M.
AU - Barry, Michael J.
AU - Nicholson, Wanda K.
AU - Cabana, Michael
AU - Chelmow, David
AU - Coker, Tumaini Rucker
AU - Davis, Esa M.
AU - Donahue, Katrina E.
AU - Jaén, Carlos Roberto
AU - Li, Li
AU - Ogedegbe, Gbenga
AU - Rao, Goutham
AU - Ruiz, John M.
AU - Stevermer, James
AU - Underwood, Sandra Millon
AU - Wong, John B.
N1 - Publisher Copyright:
© 2023 American Medical Association. All rights reserved.
PY - 2023/5/2
Y1 - 2023/5/2
N2 - Importance: In the US, tuberculosis remains an important preventable disease, including active tuberculosis, which may be infectious, and latent tuberculosis infection (LTBI), which is asymptomatic and not infectious but can later progress to active disease. The precise prevalence rate of LTBI in the US is difficult to determine; however, estimated prevalence is about 5.0%, or up to 13 million persons. Incidence of tuberculosis varies by geography and living accommodations, suggesting an association with social determinants of health. Objective: To update its 2016 recommendation, the US Preventive Services Task Force (USPSTF) commissioned a systematic review on LTBI screening and treatment in asymptomatic adults seen in primary care, as well as the accuracy of LTBI screening tests. Population: Asymptomatic adults 18 years or older at increased risk for tuberculosis. Evidence Assessment: The USPSTF concludes with moderate certainty that there is a moderate net benefit in preventing active tuberculosis disease by screening for LTBI in persons at increased risk for tuberculosis infection. Recommendation: The USPSTF recommends screening for LTBI in populations at increased risk. (B recommendation).
AB - Importance: In the US, tuberculosis remains an important preventable disease, including active tuberculosis, which may be infectious, and latent tuberculosis infection (LTBI), which is asymptomatic and not infectious but can later progress to active disease. The precise prevalence rate of LTBI in the US is difficult to determine; however, estimated prevalence is about 5.0%, or up to 13 million persons. Incidence of tuberculosis varies by geography and living accommodations, suggesting an association with social determinants of health. Objective: To update its 2016 recommendation, the US Preventive Services Task Force (USPSTF) commissioned a systematic review on LTBI screening and treatment in asymptomatic adults seen in primary care, as well as the accuracy of LTBI screening tests. Population: Asymptomatic adults 18 years or older at increased risk for tuberculosis. Evidence Assessment: The USPSTF concludes with moderate certainty that there is a moderate net benefit in preventing active tuberculosis disease by screening for LTBI in persons at increased risk for tuberculosis infection. Recommendation: The USPSTF recommends screening for LTBI in populations at increased risk. (B recommendation).
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U2 - 10.1001/jama.2023.4899
DO - 10.1001/jama.2023.4899
M3 - Review article
C2 - 37129649
AN - SCOPUS:85156221121
SN - 0098-7484
VL - 329
SP - 1487
EP - 1494
JO - JAMA - Journal of the American Medical Association
JF - JAMA - Journal of the American Medical Association
IS - 17
ER -