TY - JOUR
T1 - Roles for the sarco-/endoplasmic reticulum in cardiac myocyte contraction, protein synthesis, and protein quality control
AU - Glembotski, Christopher C.
PY - 2012/12/1
Y1 - 2012/12/1
N2 - Although the function of the sarcoplasmic/endoplasmic reticulum (SR/ER) in cardiac contractile calcium handling is well established, its roles in protein synthesis, folding, and quality control in cardiac myocytes are not as clear. This review explores evidence suggesting that, in cardiac myocytes, protein synthesis and contractile calcium handling may be physically and functionally integrated.
AB - Although the function of the sarcoplasmic/endoplasmic reticulum (SR/ER) in cardiac contractile calcium handling is well established, its roles in protein synthesis, folding, and quality control in cardiac myocytes are not as clear. This review explores evidence suggesting that, in cardiac myocytes, protein synthesis and contractile calcium handling may be physically and functionally integrated.
UR - http://www.scopus.com/inward/record.url?scp=84870822727&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84870822727&partnerID=8YFLogxK
U2 - 10.1152/physiol.00034.2012
DO - 10.1152/physiol.00034.2012
M3 - Review article
C2 - 23223628
AN - SCOPUS:84870822727
SN - 1548-9213
VL - 27
SP - 343
EP - 350
JO - Physiology
JF - Physiology
IS - 6
ER -