Electrolytic lesions of the midbrain raphe nuclei in rats, lowering serotonin level in the forebrain, elicited mouse killing behavior. After the lesion, 50% of previously non killer rats became mouse killers. 5 Hydroxytryptophan (100 mg/kg) administration elevates serotonin level to normal values and completely blocked predatory aggression. p Chlorophenylalanine produced obvious reduction in brain serotonin and slightly stimulated aggressive behavior. These results suggest that the brain serotonin participates as an inhibitory factor in mouse killing behavior in rats.
|Original language||English (US)|
|Number of pages||4|
|Journal||Fiziologicheskii Zhurnal SSSR Imeni I.M. Sechenova|
|State||Published - 1975|
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