Role of serotonin in mouse killing behavior of rats (Russian)

N. K. Popova, E. M. Nikulina, V. I. Aruv, N. N. Kudriavtseva

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Electrolytic lesions of the midbrain raphe nuclei in rats, lowering serotonin level in the forebrain, elicited mouse killing behavior. After the lesion, 50% of previously non killer rats became mouse killers. 5 Hydroxytryptophan (100 mg/kg) administration elevates serotonin level to normal values and completely blocked predatory aggression. p Chlorophenylalanine produced obvious reduction in brain serotonin and slightly stimulated aggressive behavior. These results suggest that the brain serotonin participates as an inhibitory factor in mouse killing behavior in rats.

Original languageEnglish (US)
Pages (from-to)183-186
Number of pages4
JournalFiziologicheskii Zhurnal SSSR Imeni I.M. Sechenova
Issue number2
StatePublished - 1975

ASJC Scopus subject areas

  • General Medicine


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