Role of Mouse Cytochrome P450 Enzymes of the Cyp2abfgs Subfamilies in the Induction of Lung Inflammation by Cigarette Smoke Exposure

Keyphrases

• Cigarette Smoke Exposure 100%
• Cytochrome P450 Enzymes 100%
• Lung Inflammation 100%
• Environmental Tobacco Smoke 100%
• Null Mice 50%
• Bioactivation 37%
• Bronchoalveolar Lavage Fluid 25%
• Naphthalene 25%
• Wild Mice 25%
• Tobacco Smoke Exposure 25%
• GSH Conjugate 25%
• P450 Enzymes 25%
• 3-Methylindole 25%
• Inflammatory Cytokines 12%
• Adverse Effects 12%
• Inflammatory Proteins 12%
• Cell Wall Proteins 12%
• Histological Analysis 12%
• Risk Assessment 12%
• Cytochrome P450 (CYP450) 12%
• Lung 12%
• Toxic Effects 12%
• Uncertainty Sources 12%
• Cell-free 12%
• Gene Cluster 12%
• C57BL 12%
• Glutathione 12%
• Adult Female 12%
• Tobacco Smoke 12%
• Knowledge Gaps 12%
• Chemoprevention 12%
• Chemokines 12%
• In Vivo Evidence 12%
• Inflammatory Cells 12%
• Cell Cytokines 12%
• Environmental Tobacco Smoke Exposure 12%
• Lung Toxicity 12%
• Total Protein Content 12%
• Neutrophilic Inflammation 12%
• Enzyme-mediated 12%
• Fluid Analysis 12%
• Inflammatory Chemokines 12%
• Smoke Constituents 12%

Pharmacology, Toxicology and Pharmaceutical Science

• Mouse 100%
• Cigarette Smoke 100%
• Cytochrome P450 100%
• Pneumonia 100%
• Knockout Mouse 80%
• Bioactivation 60%
• Cytokine 40%
• Wild Type Mouse 40%
• Chemokine 40%
• Naphthalene 40%
• Skatole 40%
• Protein 20%
• Adverse Event 20%
• Toxicity 20%
• Glutathione 20%
• Lung Toxicity 20%