Massive Open Online Courses (MOOCs) have created a major paradigm shift in online education by offering web-based courses at no cost to virtually anyone with access to a computer/laptop with internet connection. In 2012, MOOCs gained significant attention from media, students, educators, and entrepreneurs. It is continuing to develop into a more popular and widespread educational technology. This paper identifies and discusses few key elements of massively open online education that can influence pedagogy and learning in STEM disciplines. It also examines the potential of MOOCs in improving learning experiences and facilitating interdisciplinary education in STEM fields.