Abstract
Pressure ulcers are preventable, yet highly prevalent, chronic wounds that have significant patient morbidity and high healthcare costs. Like other chronic wounds, they are characterized by impaired wound healing due to dysregulated immune processes. This review will highlight key biochemical pathways in the pathogenesis of pressure injury and how this signaling leads to impaired wound healing. This review is the first to comprehensively describe the current literature on microRNA (miRNA, miR) regulation of pressure ulcer pathophysiology.
| Original language | English (US) |
|---|---|
| Article number | 64 |
| Pages (from-to) | 1-14 |
| Number of pages | 14 |
| Journal | International journal of molecular sciences |
| Volume | 22 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 2021 |
| Externally published | Yes |
Keywords
- Chronic wound
- MicroRNA (miRNA, miR)
- Pressure ulcer
ASJC Scopus subject areas
- Catalysis
- Molecular Biology
- Computer Science Applications
- Spectroscopy
- Physical and Theoretical Chemistry
- Organic Chemistry
- Inorganic Chemistry
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