ROC curve analysis of super high resolution video for histopathology

Kenneth J. Bloom; L. Susan Rozek; Ronald S. Weinstein

doi:10.1117/12.976532

ROC curve analysis of super high resolution video for histopathology

Kenneth J. Bloom, L. Susan Rozek, Ronald S. Weinstein

Research output: Contribution to journal › Conference article › peer-review

9 Scopus citations

Abstract

The receiver operator characteristic (ROC) curve is used to assess the ability of a diagnostic test to distinguish between two discreet states, such as tumor present or tumor absent in a histopathologic section. We have used ROC methodology to assess the ability of pathologists to diagnose frozen section biopsies of breast tissue as benign or malignant, using both a conventional light microscope and a high resolution camera/monitor system. 115 consecutive frozen section breast biopsies were reviewed using each of the above modalities. Results yielded identical ROC curves for the conventional light microscope and high resolution camera/monitor system. Furthermore, the percentage of cases in which pathologists rendered an "equivocal" diagnosis was the same with both modalities.

Original language	English (US)
Pages (from-to)	408-412
Number of pages	5
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	845
DOIs	https://doi.org/10.1117/12.976532
State	Published - Oct 13 1987
Externally published	Yes
Event	Visual Communications and Image Processing II 1987 - San Diego, United States Duration: Oct 27 1987 → Oct 29 1987

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

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10.1117/12.976532

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title = "ROC curve analysis of super high resolution video for histopathology",

abstract = "The receiver operator characteristic (ROC) curve is used to assess the ability of a diagnostic test to distinguish between two discreet states, such as tumor present or tumor absent in a histopathologic section. We have used ROC methodology to assess the ability of pathologists to diagnose frozen section biopsies of breast tissue as benign or malignant, using both a conventional light microscope and a high resolution camera/monitor system. 115 consecutive frozen section breast biopsies were reviewed using each of the above modalities. Results yielded identical ROC curves for the conventional light microscope and high resolution camera/monitor system. Furthermore, the percentage of cases in which pathologists rendered an {"}equivocal{"} diagnosis was the same with both modalities.",

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language = "English (US)",

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T1 - ROC curve analysis of super high resolution video for histopathology

AU - Bloom, Kenneth J.

AU - Rozek, L. Susan

AU - Weinstein, Ronald S.

PY - 1987/10/13

Y1 - 1987/10/13

N2 - The receiver operator characteristic (ROC) curve is used to assess the ability of a diagnostic test to distinguish between two discreet states, such as tumor present or tumor absent in a histopathologic section. We have used ROC methodology to assess the ability of pathologists to diagnose frozen section biopsies of breast tissue as benign or malignant, using both a conventional light microscope and a high resolution camera/monitor system. 115 consecutive frozen section breast biopsies were reviewed using each of the above modalities. Results yielded identical ROC curves for the conventional light microscope and high resolution camera/monitor system. Furthermore, the percentage of cases in which pathologists rendered an "equivocal" diagnosis was the same with both modalities.

AB - The receiver operator characteristic (ROC) curve is used to assess the ability of a diagnostic test to distinguish between two discreet states, such as tumor present or tumor absent in a histopathologic section. We have used ROC methodology to assess the ability of pathologists to diagnose frozen section biopsies of breast tissue as benign or malignant, using both a conventional light microscope and a high resolution camera/monitor system. 115 consecutive frozen section breast biopsies were reviewed using each of the above modalities. Results yielded identical ROC curves for the conventional light microscope and high resolution camera/monitor system. Furthermore, the percentage of cases in which pathologists rendered an "equivocal" diagnosis was the same with both modalities.

UR - https://www.scopus.com/pages/publications/0008235707

UR - https://www.scopus.com/inward/citedby.url?scp=0008235707&partnerID=8YFLogxK

U2 - 10.1117/12.976532

DO - 10.1117/12.976532

M3 - Conference article

AN - SCOPUS:0008235707

SN - 0277-786X

VL - 845

SP - 408

EP - 412

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

T2 - Visual Communications and Image Processing II 1987

Y2 - 27 October 1987 through 29 October 1987

ER -

ROC curve analysis of super high resolution video for histopathology

Abstract

ASJC Scopus subject areas

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