ROC curve analysis of super high resolution video for histopathology

Kenneth J. Bloom, L. Susan Rozek, Ronald S. Weinstein

Research output: Contribution to journalConference articlepeer-review

9 Scopus citations


The receiver operator characteristic (ROC) curve is used to assess the ability of a diagnostic test to distinguish between two discreet states, such as tumor present or tumor absent in a histopathologic section. We have used ROC methodology to assess the ability of pathologists to diagnose frozen section biopsies of breast tissue as benign or malignant, using both a conventional light microscope and a high resolution camera/monitor system. 115 consecutive frozen section breast biopsies were reviewed using each of the above modalities. Results yielded identical ROC curves for the conventional light microscope and high resolution camera/monitor system. Furthermore, the percentage of cases in which pathologists rendered an "equivocal" diagnosis was the same with both modalities.

Original languageEnglish (US)
Pages (from-to)408-412
Number of pages5
JournalProceedings of SPIE - The International Society for Optical Engineering
StatePublished - Oct 13 1987
EventVisual Communications and Image Processing II 1987 - San Diego, United States
Duration: Oct 27 1987Oct 29 1987

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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