Abstract
This chapter summarizes the roles of siRNAs and miRNAs in several common liver diseases including viral hepatitis, hepatocellular carcinoma, and liver fibrosis. Various delivery systems for siRNA and miRNA are also reviewed.
| Original language | English (US) |
|---|---|
| Title of host publication | Advanced Delivery and Therapeutic Applications of RNAi |
| Publisher | John Wiley and Sons |
| Pages | 327-366 |
| Number of pages | 40 |
| ISBN (Print) | 9781119976868 |
| DOIs | |
| State | Published - Apr 26 2013 |
| Externally published | Yes |
Keywords
- Cell-specific targeting
- HBV
- HCC
- HCV
- Lipid-based system
- Liver fibrosis
- Polymer-based system
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Pharmacology, Toxicology and Pharmaceutics(all)