TY - JOUR
T1 - Risk-reduction surgery decisions in high-risk women seen for genetic counseling
AU - Ray, Jessica A.
AU - Loescher, Lois J.
AU - Brewer, Molly
N1 - Funding Information:
The authors acknowledge the counseling contributions of Katherine Hunt, MS, CGC, and technical support from Andrea Uscinski. Funding for this project was from Phi Beta Psi (Kappa Sigma and Sigma Mu Chapters) and the Better than Ever Program at the Arizona Cancer Center. Dr. Loescher supported in part by the Oncology Nursing Foundation.
PY - 2005/12
Y1 - 2005/12
N2 - Women at greatest risk for hereditary breast and ovarian cancer may consider prophylactic removal of breasts or ovaries as a risk-reduction measure. This report describes uptake of risk-reduction mastectomy (RRM), risk-reduction oophorectomy (RRO), and related factors in 62 high-risk women who received genetic counseling. Seven (11%) participants underwent RRM and 13 (21%) underwent RRO. Of these women, 37% did not have BRCA testing, suggesting other factors influence decisions to undergo surgery. Women who had indicated (pre-genetic counseling) their intent not to have surgery chose not to have surgery. Information received during genetic counseling that women perceived as being most important for influencing risk-reduction surgery decisions was BRCA test result (positive or negative), followed by discussion of family cancer history. Reasons for indecision about risk-reduction surgery included genetic testing results, concerns about surgery, timing in life, and early menopause. The findings enhance our understanding of information that is helpful to women considering this surgery.
AB - Women at greatest risk for hereditary breast and ovarian cancer may consider prophylactic removal of breasts or ovaries as a risk-reduction measure. This report describes uptake of risk-reduction mastectomy (RRM), risk-reduction oophorectomy (RRO), and related factors in 62 high-risk women who received genetic counseling. Seven (11%) participants underwent RRM and 13 (21%) underwent RRO. Of these women, 37% did not have BRCA testing, suggesting other factors influence decisions to undergo surgery. Women who had indicated (pre-genetic counseling) their intent not to have surgery chose not to have surgery. Information received during genetic counseling that women perceived as being most important for influencing risk-reduction surgery decisions was BRCA test result (positive or negative), followed by discussion of family cancer history. Reasons for indecision about risk-reduction surgery included genetic testing results, concerns about surgery, timing in life, and early menopause. The findings enhance our understanding of information that is helpful to women considering this surgery.
KW - Decision-making
KW - Genetic counseling
KW - Genetic testing
KW - Hereditary breast/ovarian cancer
KW - Precaution adoption process
KW - Prophylactic mastectomy
KW - Prophylactic oophorectomy
KW - Risk-reduction surgery
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U2 - 10.1007/s10897-005-5833-5
DO - 10.1007/s10897-005-5833-5
M3 - Article
C2 - 16388328
AN - SCOPUS:33644634260
VL - 14
SP - 473
EP - 484
JO - Journal of Genetic Counseling
JF - Journal of Genetic Counseling
SN - 1059-7700
IS - 6
ER -