Risk factors for disseminated coccidioidomycosis, United States

Camila D. Odio; Beatriz E. Marciano; John N. Galgiani; Steven M. Holland

doi:10.3201/eid2302.160505

Risk factors for disseminated coccidioidomycosis, United States

Camila D. Odio, Beatriz E. Marciano, John N. Galgiani, Steven M. Holland

Research output: Contribution to journal › Article › peer-review

114 Scopus citations

Abstract

Of 150,000 new coccidioidomycosis infections that occur annually in the United States, ≈1% disseminate; one third of those cases are fatal. Immunocompromised hosts have higher rates of dissemination. We identified 8 patients with disseminated coccidioidomycosis who had defects in the interleukin-12/interferon-γ and STAT3 axes, indicating that these are critical host defense pathways.

Original language	English (US)
Pages (from-to)	308-311
Number of pages	4
Journal	Emerging infectious diseases
Volume	23
Issue number	2
DOIs	https://doi.org/10.3201/eid2302.160505
State	Published - Feb 2017

ASJC Scopus subject areas

Epidemiology
Microbiology (medical)
Infectious Diseases

Access to Document

10.3201/eid2302.160505

Cite this

@article{847ca57ad2154d2fbdf4db26361d43c9,

title = "Risk factors for disseminated coccidioidomycosis, United States",

abstract = "Of 150,000 new coccidioidomycosis infections that occur annually in the United States, ≈1% disseminate; one third of those cases are fatal. Immunocompromised hosts have higher rates of dissemination. We identified 8 patients with disseminated coccidioidomycosis who had defects in the interleukin-12/interferon-γ and STAT3 axes, indicating that these are critical host defense pathways.",

author = "Odio, {Camila D.} and Marciano, {Beatriz E.} and Galgiani, {John N.} and Holland, {Steven M.}",

note = "Funding Information: This study was funded in part by the Division of Intramural Research of the National Institute of Allergy and Infectious Diseases National Institutes of Health (NIH), USA. Publisher Copyright: {\textcopyright} 2017, Centers for Disease Control and Prevention (CDC). All rights reserved.",

year = "2017",

month = feb,

doi = "10.3201/eid2302.160505",

language = "English (US)",

volume = "23",

pages = "308--311",

journal = "Emerging infectious diseases",

issn = "1080-6040",

publisher = "Centers for Disease Control and Prevention (CDC)",

number = "2",

}

TY - JOUR

T1 - Risk factors for disseminated coccidioidomycosis, United States

AU - Odio, Camila D.

AU - Marciano, Beatriz E.

AU - Galgiani, John N.

AU - Holland, Steven M.

N1 - Funding Information: This study was funded in part by the Division of Intramural Research of the National Institute of Allergy and Infectious Diseases National Institutes of Health (NIH), USA. Publisher Copyright: © 2017, Centers for Disease Control and Prevention (CDC). All rights reserved.

PY - 2017/2

Y1 - 2017/2

N2 - Of 150,000 new coccidioidomycosis infections that occur annually in the United States, ≈1% disseminate; one third of those cases are fatal. Immunocompromised hosts have higher rates of dissemination. We identified 8 patients with disseminated coccidioidomycosis who had defects in the interleukin-12/interferon-γ and STAT3 axes, indicating that these are critical host defense pathways.

AB - Of 150,000 new coccidioidomycosis infections that occur annually in the United States, ≈1% disseminate; one third of those cases are fatal. Immunocompromised hosts have higher rates of dissemination. We identified 8 patients with disseminated coccidioidomycosis who had defects in the interleukin-12/interferon-γ and STAT3 axes, indicating that these are critical host defense pathways.

UR - http://www.scopus.com/inward/record.url?scp=85009976274&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85009976274&partnerID=8YFLogxK

U2 - 10.3201/eid2302.160505

DO - 10.3201/eid2302.160505

M3 - Article

C2 - 28098554

AN - SCOPUS:85009976274

SN - 1080-6040

VL - 23

SP - 308

EP - 311

JO - Emerging infectious diseases

JF - Emerging infectious diseases

IS - 2

ER -

Risk factors for disseminated coccidioidomycosis, United States

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this