TY - JOUR
T1 - Risk factors for above-knee amputations in diabetes mellitus
AU - Van Houtum, William H.
AU - Lavery, Lawrence A.
AU - Armstrong, David G.
PY - 1998/7
Y1 - 1998/7
N2 - Background. Above-knee amputation (AKA) is a common complication in diabetics, mostly after one or more lower level amputations (LEAs) have been done. The aim of this study was to identify risk factors for AKAs among diabetics. Methods. We abstracted 1,800 medical records of hospitalizations for LEA. Kaplan's comorbidity classification was used to rank disease severity. We used both univariate and multivariate models to identify risk factors for AKA. Results. Of the 1,043 diabetic amputees in this study, 22% had AKA. Variables associated with AKA were locomotor impairment, severe anemia, history of lower extremity bypass surgery, body mass index (BMI) <20 kg/m2, female sex, cerebrovascular disease, cardiovascular disease, and SGOT >40 U/L. Conclusions. Most of these risk factors represent end-stage processes and do not have good treatment alternatives. Perhaps one of the practical applications of these data is not to describe risk of proximal amputations but instead to look more closely at candidates who should be considered for distal procedures.
AB - Background. Above-knee amputation (AKA) is a common complication in diabetics, mostly after one or more lower level amputations (LEAs) have been done. The aim of this study was to identify risk factors for AKAs among diabetics. Methods. We abstracted 1,800 medical records of hospitalizations for LEA. Kaplan's comorbidity classification was used to rank disease severity. We used both univariate and multivariate models to identify risk factors for AKA. Results. Of the 1,043 diabetic amputees in this study, 22% had AKA. Variables associated with AKA were locomotor impairment, severe anemia, history of lower extremity bypass surgery, body mass index (BMI) <20 kg/m2, female sex, cerebrovascular disease, cardiovascular disease, and SGOT >40 U/L. Conclusions. Most of these risk factors represent end-stage processes and do not have good treatment alternatives. Perhaps one of the practical applications of these data is not to describe risk of proximal amputations but instead to look more closely at candidates who should be considered for distal procedures.
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U2 - 10.1097/00007611-199807000-00007
DO - 10.1097/00007611-199807000-00007
M3 - Article
C2 - 9671835
AN - SCOPUS:0031818156
SN - 0038-4348
VL - 91
SP - 643
EP - 648
JO - Southern Medical Journal
JF - Southern Medical Journal
IS - 7
ER -