Ribosome-lamellae complexes in benign plasma cells accompanying neoplastic infiltrates

K. G. Zimmerman, C. M. Payne, R. B. Nagle

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Two examples of ribosome-lamellae complexes (RLCs) occurring in benign plasma cells are presented. These were seen utilizing transmission electron microscopy in a case of mycosis fungoides in skin and a fibrosarcoma of a lower extremity. In both cases the accompanying plasmacytic infiltrate was interpreted as reactive and not malignant. Once thought to be a specific marker for hairy cell leukemia. RLCs now have been described in a wide variety of neoplastic diseases (mostly hematologic) and in a few examples of nonneoplastic conditions. RLCs have not been described previously in benign plasma cells. A review of the literature with respect to occurrence and significance of RLCs is presented.

Original languageEnglish (US)
Pages (from-to)364-367
Number of pages4
JournalAmerican journal of clinical pathology
Issue number3
StatePublished - 1984

ASJC Scopus subject areas

  • Pathology and Forensic Medicine


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