Reuse of a previously transplanted kidney: Does success come with a price?

Pradeep V. Kadambi, W. James Chon, Michelle A. Josephson, Amishi Desai, J. Richard Thistlethwaite, Robert C. Harland, Shane M. Meehan, Marc R. Garfinkel

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Longer wait times for deceased donor kidney transplant have prompted newer initiatives to expedite the process. Reuse of a previously transplanted kidney might be appropriate in certain circumstances. However, one must also consider the unique issues that may arise after such transplants. We describe our experience in one such case where the donor kidney had lesions of focal and segmental glomerulosclerosis and signs of alloreactivity (positive C4d staining) prior to transplantation and the recipient developed ganciclovir-resistant cytomegalovirus (CMV) infection, which was perhaps transmitted from the donor. Despite the challenges, the allograft function remained stable 5 years after reuse.

Original languageEnglish (US)
Pages (from-to)434-437
Number of pages4
JournalClinical Kidney Journal
Volume5
Issue number5
DOIs
StatePublished - Oct 2012
Externally publishedYes

Keywords

  • cytomegalovirus (CMV)
  • ganciclovir resistance
  • organ reuse
  • rejection

ASJC Scopus subject areas

  • Nephrology
  • Transplantation

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