Retardation by the soybean Bowman-Birk inhibitor of elastin hydrolysis catalyzed by leukocyte proteinases

Tamara V. Tikhonova, Inna P. Gladysheva, Natalia I. Larionova

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

The classical Bowman-Birk inhibitor from soya retards strongly the hydrolysis of elastin catalyzed by leukocyte elastase, cathepsin G and a mixture of both. The inhibitory effect is practically unaffected by both the adsorption of the enzymes on elastin and prolongation of the enzymatic reaction.

Original languageEnglish (US)
Pages (from-to)225-228
Number of pages4
JournalFEBS Letters
Volume362
Issue number2
DOIs
StatePublished - Apr 3 1995
Externally publishedYes

Keywords

  • Bowman-Birk soybean inhibitor
  • Elastin
  • Human leukocyte cathepsin G
  • Human leukocyte elastase

ASJC Scopus subject areas

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology

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