Response of malignant melanoma to plasma exchange, surgical debulking, and Corynebacterium parvum

J. C. Bottino; R. D. Rossen; E. M. Hersh; A. Rios; J. P. Hester; C. M. McBride

Response of malignant melanoma to plasma exchange, surgical debulking, and Corynebacterium parvum

J. C. Bottino, R. D. Rossen, E. M. Hersh, A. Rios, J. P. Hester, C. M. McBride

Research output: Contribution to journal › Article › peer-review

Abstract

A 48 year old man with extensive cutaneous and subcutaneous metastatic malignant melanoma responded to treatment by repeated plasma exchanges, partial surgical debulking of tumor masses, and intravenous Corynebacterium parvum. Circulating immune complexes were measured by the serum C1(q) binding method. Tumor regression coincided with serum C1(q) binding reduction to normal levels. Clinical relapse was preceded by recurrent elevation of serum C1(q) binding activity.

Original language	English (US)
Pages (from-to)	53-57
Number of pages	5
Journal	International Journal of Artificial Organs
Volume	1
Issue number	1
State	Published - 1978
Externally published	Yes

ASJC Scopus subject areas

Bioengineering
Medicine (miscellaneous)
Biomaterials
Biomedical Engineering

Cite this

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title = "Response of malignant melanoma to plasma exchange, surgical debulking, and Corynebacterium parvum",

abstract = "A 48 year old man with extensive cutaneous and subcutaneous metastatic malignant melanoma responded to treatment by repeated plasma exchanges, partial surgical debulking of tumor masses, and intravenous Corynebacterium parvum. Circulating immune complexes were measured by the serum C1(q) binding method. Tumor regression coincided with serum C1(q) binding reduction to normal levels. Clinical relapse was preceded by recurrent elevation of serum C1(q) binding activity.",

author = "Bottino, {J. C.} and Rossen, {R. D.} and Hersh, {E. M.} and A. Rios and Hester, {J. P.} and McBride, {C. M.}",

year = "1978",

language = "English (US)",

volume = "1",

pages = "53--57",

journal = "International Journal of Artificial Organs",

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T1 - Response of malignant melanoma to plasma exchange, surgical debulking, and Corynebacterium parvum

AU - Bottino, J. C.

AU - Rossen, R. D.

AU - Hersh, E. M.

AU - Rios, A.

AU - Hester, J. P.

AU - McBride, C. M.

PY - 1978

Y1 - 1978

N2 - A 48 year old man with extensive cutaneous and subcutaneous metastatic malignant melanoma responded to treatment by repeated plasma exchanges, partial surgical debulking of tumor masses, and intravenous Corynebacterium parvum. Circulating immune complexes were measured by the serum C1(q) binding method. Tumor regression coincided with serum C1(q) binding reduction to normal levels. Clinical relapse was preceded by recurrent elevation of serum C1(q) binding activity.

AB - A 48 year old man with extensive cutaneous and subcutaneous metastatic malignant melanoma responded to treatment by repeated plasma exchanges, partial surgical debulking of tumor masses, and intravenous Corynebacterium parvum. Circulating immune complexes were measured by the serum C1(q) binding method. Tumor regression coincided with serum C1(q) binding reduction to normal levels. Clinical relapse was preceded by recurrent elevation of serum C1(q) binding activity.

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AN - SCOPUS:0018060085

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JO - International Journal of Artificial Organs

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IS - 1

ER -

Response of malignant melanoma to plasma exchange, surgical debulking, and Corynebacterium parvum

Abstract

ASJC Scopus subject areas

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