TY - JOUR
T1 - Respirator physiologic impact in persons with mild respiratory disease
AU - Harber, Philip
AU - Santiago, Silverio
AU - Wu, Samantha
AU - Bansal, Siddharth
AU - Liu, Yihang
AU - Yun, David
PY - 2010/2
Y1 - 2010/2
N2 - Objective: To assess whether mild respiratory disease affects physiologic adaptation to respirator use. Methods: The study compared the respiratory effects of dual cartridge half face mask and filtering facepeice (N95) respirators while performing simulated-work tasks. Subjects with mild chronic obstructive pulmonary disease (n = 14), asthma (n = 42), chronic rhinitis (n = 17), and normal respiratory status (n = 24) were studied. Mixed model regression analyses determined the effects of respirator type, disease status, and the respirator-disease interactions. Results: Respirator type significantly affected several physiologic measures. Respirator type effects differed among disease categories as shown by statistically significant interaction terms. Respiratory timing parameters were more affected than ventilatory volumes. In general, persons with asthma showed greater respirator-disease interactions than chronic obstructive pulmonary disease, rhinitis, or healthy subjects. Conclusions: The effects of respirator type differ according to the category of respiratory disease.
AB - Objective: To assess whether mild respiratory disease affects physiologic adaptation to respirator use. Methods: The study compared the respiratory effects of dual cartridge half face mask and filtering facepeice (N95) respirators while performing simulated-work tasks. Subjects with mild chronic obstructive pulmonary disease (n = 14), asthma (n = 42), chronic rhinitis (n = 17), and normal respiratory status (n = 24) were studied. Mixed model regression analyses determined the effects of respirator type, disease status, and the respirator-disease interactions. Results: Respirator type significantly affected several physiologic measures. Respirator type effects differed among disease categories as shown by statistically significant interaction terms. Respiratory timing parameters were more affected than ventilatory volumes. In general, persons with asthma showed greater respirator-disease interactions than chronic obstructive pulmonary disease, rhinitis, or healthy subjects. Conclusions: The effects of respirator type differ according to the category of respiratory disease.
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U2 - 10.1097/JOM.0b013e3181ca0ec9
DO - 10.1097/JOM.0b013e3181ca0ec9
M3 - Article
C2 - 20134350
AN - SCOPUS:77049086372
SN - 1076-2752
VL - 52
SP - 155
EP - 162
JO - Journal of occupational and environmental medicine
JF - Journal of occupational and environmental medicine
IS - 2
ER -