TY - JOUR
T1 - Resistin and Cardiovascular Disease
AU - Ding, Qinxue
AU - White, Sharla Powell
AU - Ling, Christina
AU - Zhou, Wei
PY - 2011/1
Y1 - 2011/1
N2 - Resistin has been implicated in coronary atherosclerotic disease and congestive heart failure. Recent studies have extended its involvement in peripheral artery disease. Despite some controversial data, the mainstream clinical literature supports that resistin is associated with both coronary and peripheral artery diseases including ischemic stroke. In this review, the multiple roles of resistin as screening, diagnostic, and prognostic marker for cardiovascular disease are discussed. The independence of resistin in disease prediction and diagnosis appears complicated by its confounders, such as C-reactive protein. A clear-cut biomarker function of resistin in cardiovascular disease needs be clarified by additional large-scale, well-designed prospective studies.
AB - Resistin has been implicated in coronary atherosclerotic disease and congestive heart failure. Recent studies have extended its involvement in peripheral artery disease. Despite some controversial data, the mainstream clinical literature supports that resistin is associated with both coronary and peripheral artery diseases including ischemic stroke. In this review, the multiple roles of resistin as screening, diagnostic, and prognostic marker for cardiovascular disease are discussed. The independence of resistin in disease prediction and diagnosis appears complicated by its confounders, such as C-reactive protein. A clear-cut biomarker function of resistin in cardiovascular disease needs be clarified by additional large-scale, well-designed prospective studies.
UR - http://www.scopus.com/inward/record.url?scp=84859504735&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84859504735&partnerID=8YFLogxK
U2 - 10.1016/j.tcm.2012.01.004
DO - 10.1016/j.tcm.2012.01.004
M3 - Review article
C2 - 22498016
AN - SCOPUS:84859504735
SN - 1050-1738
VL - 21
SP - 20
EP - 27
JO - Trends in Cardiovascular Medicine
JF - Trends in Cardiovascular Medicine
IS - 1
ER -