Resistin and Cardiovascular Disease

Qinxue Ding, Sharla Powell White, Christina Ling, Wei Zhou

Research output: Contribution to journalReview articlepeer-review

28 Scopus citations

Abstract

Resistin has been implicated in coronary atherosclerotic disease and congestive heart failure. Recent studies have extended its involvement in peripheral artery disease. Despite some controversial data, the mainstream clinical literature supports that resistin is associated with both coronary and peripheral artery diseases including ischemic stroke. In this review, the multiple roles of resistin as screening, diagnostic, and prognostic marker for cardiovascular disease are discussed. The independence of resistin in disease prediction and diagnosis appears complicated by its confounders, such as C-reactive protein. A clear-cut biomarker function of resistin in cardiovascular disease needs be clarified by additional large-scale, well-designed prospective studies.

Original languageEnglish (US)
Pages (from-to)20-27
Number of pages8
JournalTrends in Cardiovascular Medicine
Volume21
Issue number1
DOIs
StatePublished - Jan 2011
Externally publishedYes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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