TY - JOUR
T1 - Resection of Lung Metastases From Soft-Tissue Sarcomas
T2 - A Multivariate Analysis
AU - Verazin, Gary T.
AU - Warneke, James A.
AU - Driscoll, Deborah L.
AU - Karakousis, Constantine
AU - Petrelli, Nicholas J.
AU - Takita, Hiroshi
PY - 1992/12
Y1 - 1992/12
N2 - From 1970 through 1986, 78 patients underwent 162 thoracotomies for removal of lung metastases from soft-tissue sarcomas. A multivariate analysis showed that the presence of a local recurrence, an incomplete pulmonary resection, and a shorter disease-free interval were poor prognostic factors. Patients who underwent multiple thoracotomies survived longer from the time of initial thoracotomy. The histologic type of sarcoma and the number of metastases resected showed no statistical significance. The median survival of the 61 patients who had a complete resection was 21 months. Patients with five or fewer metastases resected had an overall 5-year survival of 22% compared with 21% for patients who had six or more metastases resected. However, patients with five or fewer metastases showed a trend toward a higher 10-year disease-free survival. A complete resection of pulmonary metastases from soft-tissue sarcoma can prolong survival even if multiple metastases are present, although patients with fewer metastases may have a longer disease-free survival.
AB - From 1970 through 1986, 78 patients underwent 162 thoracotomies for removal of lung metastases from soft-tissue sarcomas. A multivariate analysis showed that the presence of a local recurrence, an incomplete pulmonary resection, and a shorter disease-free interval were poor prognostic factors. Patients who underwent multiple thoracotomies survived longer from the time of initial thoracotomy. The histologic type of sarcoma and the number of metastases resected showed no statistical significance. The median survival of the 61 patients who had a complete resection was 21 months. Patients with five or fewer metastases resected had an overall 5-year survival of 22% compared with 21% for patients who had six or more metastases resected. However, patients with five or fewer metastases showed a trend toward a higher 10-year disease-free survival. A complete resection of pulmonary metastases from soft-tissue sarcoma can prolong survival even if multiple metastases are present, although patients with fewer metastases may have a longer disease-free survival.
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U2 - 10.1001/archsurg.1992.01420120041007
DO - 10.1001/archsurg.1992.01420120041007
M3 - Article
C2 - 1365685
AN - SCOPUS:0026448412
SN - 0004-0010
VL - 127
SP - 1407
EP - 1411
JO - Archives of Surgery
JF - Archives of Surgery
IS - 12
ER -