TY - JOUR
T1 - Reproductive health effects of aflatoxins
T2 - A review of the literature
AU - Shuaib, Faisal M.B.
AU - Ehiri, John
AU - Abdullahi, Amina
AU - Williams, Jonathan H.
AU - Jolly, Pauline E.
N1 - Funding Information:
This research was partially supported by Agreement ECG-A-00-0700001-00 to the Peanut Collaborative Research Support Program located at the University of Georgia. USAID had no involvement in research, manuscript preparation or decision to submit the paper for publication.
PY - 2010/6
Y1 - 2010/6
N2 - Context: Although it is known that aflatoxins have many adverse health effects, there is no systematic summary of how it affects the reproductive system or its reproductive health effects. Objective: Summarize evidence on the reproductive health effects of aflatoxins. Results: The search yielded 121 potential studies, of which 25 were retained. One study found a higher concentration of aflatoxins in the semen of infertile men (40% of cases compared to 8% of controls). Six studies found significant associations or correlations between low birth weight and aflatoxins while one study did not find any correlation. One study found maternal serum aflatoxin to be a risk factor for jaundice in infants (OR, 2.68; CI, 1.18-6.10). Overall, maternal breast milk in developing countries had higher rates of aflatoxin contamination than in high income countries. Conclusions: Stakeholders in developing countries need to take steps to reduce exposure of vulnerable populations to the toxic effects of aflatoxins.
AB - Context: Although it is known that aflatoxins have many adverse health effects, there is no systematic summary of how it affects the reproductive system or its reproductive health effects. Objective: Summarize evidence on the reproductive health effects of aflatoxins. Results: The search yielded 121 potential studies, of which 25 were retained. One study found a higher concentration of aflatoxins in the semen of infertile men (40% of cases compared to 8% of controls). Six studies found significant associations or correlations between low birth weight and aflatoxins while one study did not find any correlation. One study found maternal serum aflatoxin to be a risk factor for jaundice in infants (OR, 2.68; CI, 1.18-6.10). Overall, maternal breast milk in developing countries had higher rates of aflatoxin contamination than in high income countries. Conclusions: Stakeholders in developing countries need to take steps to reduce exposure of vulnerable populations to the toxic effects of aflatoxins.
KW - Aflatoxins
KW - Aflatoxins and birth outcomes
KW - Aflatoxins and breast milk
KW - Reproductive health outcomes
UR - http://www.scopus.com/inward/record.url?scp=77951622764&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77951622764&partnerID=8YFLogxK
U2 - 10.1016/j.reprotox.2009.12.005
DO - 10.1016/j.reprotox.2009.12.005
M3 - Review article
C2 - 20045048
AN - SCOPUS:77951622764
SN - 0890-6238
VL - 29
SP - 262
EP - 270
JO - Reproductive Toxicology
JF - Reproductive Toxicology
IS - 3
ER -