Renal tubular transport of calcium and phosphate in snakes: Role of calcitonin

Nancy B. Clark; William H. Dantzler

doi:10.1016/0016-6480(75)90085-4

Renal tubular transport of calcium and phosphate in snakes: Role of calcitonin

Nancy B. Clark, William H. Dantzler

Physiology

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Abstract

The effect of acute doses of salmon or porcine calcitonin upon serum values and renal excretion of calcium and phosphate was studied in sham-operated or parathyroidectomized water snakes of the genus Natrix. In intact animals, calcitonin appeared to have no significant effect upon the serum values or the renal clearance of phosphate. In the parathyroidectomized animals, calcitonin caused a depression of serum phosphate values and a slight increase in relative renal phosphate clearance ( C_PO₄ C_In). Calcium values and glomerular filtration rates were not altered in either group. The effect of calcitonin upon phosphate excretion in snakes seems to be of minimal importance compared to that of parathyroid hormone.

Original language	English (US)
Pages (from-to)	321-326
Number of pages	6
Journal	General and comparative endocrinology
Volume	26
Issue number	3
DOIs	https://doi.org/10.1016/0016-6480(75)90085-4
State	Published - Jul 1975

ASJC Scopus subject areas

Animal Science and Zoology
Endocrinology

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10.1016/0016-6480(75)90085-4

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title = "Renal tubular transport of calcium and phosphate in snakes: Role of calcitonin",

abstract = "The effect of acute doses of salmon or porcine calcitonin upon serum values and renal excretion of calcium and phosphate was studied in sham-operated or parathyroidectomized water snakes of the genus Natrix. In intact animals, calcitonin appeared to have no significant effect upon the serum values or the renal clearance of phosphate. In the parathyroidectomized animals, calcitonin caused a depression of serum phosphate values and a slight increase in relative renal phosphate clearance ( CPO4 CIn). Calcium values and glomerular filtration rates were not altered in either group. The effect of calcitonin upon phosphate excretion in snakes seems to be of minimal importance compared to that of parathyroid hormone.",

author = "Clark, {Nancy B.} and Dantzler, {William H.}",

note = "Funding Information: We acknowledge the excellent technical assistance of Mrs. Nancy Becker and Miss Nancy Raducha. This study was supported by Grants GB 28553X (to N.B.C.) and GB 38033 (to W.H.D.) from the National Science Foundation.",

year = "1975",

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doi = "10.1016/0016-6480(75)90085-4",

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journal = "General and comparative endocrinology",

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T1 - Renal tubular transport of calcium and phosphate in snakes

T2 - Role of calcitonin

AU - Clark, Nancy B.

AU - Dantzler, William H.

N1 - Funding Information: We acknowledge the excellent technical assistance of Mrs. Nancy Becker and Miss Nancy Raducha. This study was supported by Grants GB 28553X (to N.B.C.) and GB 38033 (to W.H.D.) from the National Science Foundation.

PY - 1975/7

Y1 - 1975/7

N2 - The effect of acute doses of salmon or porcine calcitonin upon serum values and renal excretion of calcium and phosphate was studied in sham-operated or parathyroidectomized water snakes of the genus Natrix. In intact animals, calcitonin appeared to have no significant effect upon the serum values or the renal clearance of phosphate. In the parathyroidectomized animals, calcitonin caused a depression of serum phosphate values and a slight increase in relative renal phosphate clearance ( CPO4 CIn). Calcium values and glomerular filtration rates were not altered in either group. The effect of calcitonin upon phosphate excretion in snakes seems to be of minimal importance compared to that of parathyroid hormone.

AB - The effect of acute doses of salmon or porcine calcitonin upon serum values and renal excretion of calcium and phosphate was studied in sham-operated or parathyroidectomized water snakes of the genus Natrix. In intact animals, calcitonin appeared to have no significant effect upon the serum values or the renal clearance of phosphate. In the parathyroidectomized animals, calcitonin caused a depression of serum phosphate values and a slight increase in relative renal phosphate clearance ( CPO4 CIn). Calcium values and glomerular filtration rates were not altered in either group. The effect of calcitonin upon phosphate excretion in snakes seems to be of minimal importance compared to that of parathyroid hormone.

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JO - General and comparative endocrinology

JF - General and comparative endocrinology

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ER -

Renal tubular transport of calcium and phosphate in snakes: Role of calcitonin

Abstract

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