Zur Relevanz des histopathologischen Gradings beim Coloncarcinom.

Translated title of the contribution: Relevance of histopathologic grading in colonic cancer

B. Mentges, H. J. Rumpelt, R. Brückner, R. Grüssner, E. M. Risse-Eissfeller

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


The histopathological grading exerted a significant influence on prognosis in patients with colonic carcinoma. More than half of the well differentiated tumors were found in early stage pT1-3 N0 M0 compared to 25% of the G2- and 10% of the G3-tumors. The percentage of incurable cases in G2-tumors was twice as high and in G3-tumors three times as high as in patients with well differentiated carcinomas. The recurrence rate increased significantly with decreasing tumor differentiation from 21% to 51%. Despite the correlation with tumor stage the histopathological grading could be established as an independent prognostic variable and had an influence on the recurrence rate especially within tumor stage pT1-3 N0 M0.

Translated title of the contributionRelevance of histopathologic grading in colonic cancer
Original languageGerman
Pages (from-to)425-431
Number of pages7
JournalDer Chirurg; Zeitschrift für alle Gebiete der operativen Medizen
Issue number6
StatePublished - Jun 1988
Externally publishedYes

ASJC Scopus subject areas

  • Surgery


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