Abstract
The histopathological grading exerted a significant influence on prognosis in patients with colonic carcinoma. More than half of the well differentiated tumors were found in early stage pT1-3 N0 M0 compared to 25% of the G2- and 10% of the G3-tumors. The percentage of incurable cases in G2-tumors was twice as high and in G3-tumors three times as high as in patients with well differentiated carcinomas. The recurrence rate increased significantly with decreasing tumor differentiation from 21% to 51%. Despite the correlation with tumor stage the histopathological grading could be established as an independent prognostic variable and had an influence on the recurrence rate especially within tumor stage pT1-3 N0 M0.
| Translated title of the contribution | Relevance of histopathologic grading in colonic cancer |
|---|---|
| Original language | German |
| Pages (from-to) | 425-431 |
| Number of pages | 7 |
| Journal | Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen |
| Volume | 59 |
| Issue number | 6 |
| State | Published - Jun 1988 |
| Externally published | Yes |
ASJC Scopus subject areas
- Surgery