Redefining actin dynamics of the pointed-end complex in striated muscle

Jessika Iwanski, Carol C. Gregorio, Mert Colpan

Research output: Contribution to journalShort surveypeer-review

1 Scopus citations

Abstract

Striated muscle is intricately designed to provide efficient and powerful muscle contractions. Recently, a long sought-after missing component of the thin filament pointed-end machinery was discovered: cyclase-associated protein 2 (CAP2). CAP2 was identified as a crucial contributor to actin polymerization, striated muscle development, and severe muscle disease when mutated.

Original languageEnglish (US)
Pages (from-to)708-711
Number of pages4
JournalTrends in Cell Biology
Volume31
Issue number9
DOIs
StatePublished - Sep 2021

Keywords

  • actin
  • muscle
  • myopathy
  • sarcomere
  • thin filament

ASJC Scopus subject areas

  • Cell Biology

Fingerprint

Dive into the research topics of 'Redefining actin dynamics of the pointed-end complex in striated muscle'. Together they form a unique fingerprint.

Cite this