Red cell superoxide dismutase is increased in iron deficiency anemia

Lennart T. Jansson; Mikko V. Perkkiö; Wayne T. Willis; Canio J. Refino; Peter R. Dallman

doi:10.1159/000206222

Red cell superoxide dismutase is increased in iron deficiency anemia

Lennart T. Jansson
, Mikko V. Perkkiö
, Wayne T. Willis
, Canio J. Refino
, Peter R. Dallman

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

Red blood cells (RBC) from iron-deficient rats were found to generate more malonyldialdehyde after in vitro incubation with H₂O₂ than RBC from control rats (p < 0.001). The iron-deficient RBC, however, had a higher content of superoxide dismutase (SOD) than control RBC (p < 0.02). This finding suggests an increased formation of SOD compensatory to an increased oxidant stress.

Original language	English (US)
Pages (from-to)	218-221
Number of pages	4
Journal	Acta Haematologica
Volume	74
Issue number	4
DOIs	https://doi.org/10.1159/000206222
State	Published - 1985
Externally published	Yes

Keywords

Anemia
Iron deficiency
Superoxide dismutase

ASJC Scopus subject areas

Hematology

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10.1159/000206222

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title = "Red cell superoxide dismutase is increased in iron deficiency anemia",

abstract = "Red blood cells (RBC) from iron-deficient rats were found to generate more malonyldialdehyde after in vitro incubation with H2O2 than RBC from control rats (p < 0.001). The iron-deficient RBC, however, had a higher content of superoxide dismutase (SOD) than control RBC (p < 0.02). This finding suggests an increased formation of SOD compensatory to an increased oxidant stress.",

keywords = "Anemia, Iron deficiency, Superoxide dismutase",

author = "Jansson, \{Lennart T.\} and Perkki{\"o}, \{Mikko V.\} and Willis, \{Wayne T.\} and Refino, \{Canio J.\} and Dallman, \{Peter R.\}",

year = "1985",

doi = "10.1159/000206222",

language = "English (US)",

volume = "74",

pages = "218--221",

journal = "Acta Haematologica",

issn = "0001-5792",

publisher = "S. Karger AG",

number = "4",

}

TY - JOUR

T1 - Red cell superoxide dismutase is increased in iron deficiency anemia

AU - Jansson, Lennart T.

AU - Perkkiö, Mikko V.

AU - Willis, Wayne T.

AU - Refino, Canio J.

AU - Dallman, Peter R.

PY - 1985

Y1 - 1985

N2 - Red blood cells (RBC) from iron-deficient rats were found to generate more malonyldialdehyde after in vitro incubation with H2O2 than RBC from control rats (p < 0.001). The iron-deficient RBC, however, had a higher content of superoxide dismutase (SOD) than control RBC (p < 0.02). This finding suggests an increased formation of SOD compensatory to an increased oxidant stress.

AB - Red blood cells (RBC) from iron-deficient rats were found to generate more malonyldialdehyde after in vitro incubation with H2O2 than RBC from control rats (p < 0.001). The iron-deficient RBC, however, had a higher content of superoxide dismutase (SOD) than control RBC (p < 0.02). This finding suggests an increased formation of SOD compensatory to an increased oxidant stress.

KW - Anemia

KW - Iron deficiency

KW - Superoxide dismutase

UR - https://www.scopus.com/pages/publications/0022189589

UR - https://www.scopus.com/pages/publications/0022189589#tab=citedBy

U2 - 10.1159/000206222

DO - 10.1159/000206222

M3 - Article

C2 - 3939064

AN - SCOPUS:0022189589

SN - 0001-5792

VL - 74

SP - 218

EP - 221

JO - Acta Haematologica

JF - Acta Haematologica

IS - 4

ER -

Red cell superoxide dismutase is increased in iron deficiency anemia

Abstract

Keywords

ASJC Scopus subject areas

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