Red cell superoxide dismutase is increased in iron deficiency anemia

Lennart T. Jansson, Mikko V. Perkkiö, Wayne T. Willis, Canio J. Refino, Peter R. Dallman

Research output: Contribution to journalArticlepeer-review

40 Scopus citations


Red blood cells (RBC) from iron-deficient rats were found to generate more malonyldialdehyde after in vitro incubation with H2O2 than RBC from control rats (p < 0.001). The iron-deficient RBC, however, had a higher content of superoxide dismutase (SOD) than control RBC (p < 0.02). This finding suggests an increased formation of SOD compensatory to an increased oxidant stress.

Original languageEnglish (US)
Pages (from-to)218-221
Number of pages4
JournalActa Haematologica
Issue number4
StatePublished - 1985
Externally publishedYes


  • Anemia
  • Iron deficiency
  • Superoxide dismutase

ASJC Scopus subject areas

  • Hematology


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