RecA kicks Pol V into gear

Joann B. Sweasy

doi:10.1038/nsmb0305-215

RecA kicks Pol V into gear

Joann B. Sweasy

Research output: Contribution to journal › Short survey › peer-review

4 Scopus citations

Abstract

Although RecA filaments are required for genetic recombination, it now seems that they are not required for translesion synthesis and that they actually inhibit this process. This finding along with elegant biochemical studies of mutant proteins moves us closer to discerning the direct role of RecA protein in SOS mutagenesis.

Original language	English (US)
Pages (from-to)	215-216
Number of pages	2
Journal	Nature Structural and Molecular Biology
Volume	12
Issue number	3
DOIs	https://doi.org/10.1038/nsmb0305-215
State	Published - 2005
Externally published	Yes

ASJC Scopus subject areas

Structural Biology
Molecular Biology

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10.1038/nsmb0305-215

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title = "RecA kicks Pol V into gear",

abstract = "Although RecA filaments are required for genetic recombination, it now seems that they are not required for translesion synthesis and that they actually inhibit this process. This finding along with elegant biochemical studies of mutant proteins moves us closer to discerning the direct role of RecA protein in SOS mutagenesis.",

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N2 - Although RecA filaments are required for genetic recombination, it now seems that they are not required for translesion synthesis and that they actually inhibit this process. This finding along with elegant biochemical studies of mutant proteins moves us closer to discerning the direct role of RecA protein in SOS mutagenesis.

AB - Although RecA filaments are required for genetic recombination, it now seems that they are not required for translesion synthesis and that they actually inhibit this process. This finding along with elegant biochemical studies of mutant proteins moves us closer to discerning the direct role of RecA protein in SOS mutagenesis.

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U2 - 10.1038/nsmb0305-215

DO - 10.1038/nsmb0305-215

M3 - Short survey

C2 - 15744322

AN - SCOPUS:17844363724

SN - 1545-9993

VL - 12

SP - 215

EP - 216

JO - Nature Structural and Molecular Biology

JF - Nature Structural and Molecular Biology

IS - 3

ER -

RecA kicks Pol V into gear

Abstract

ASJC Scopus subject areas

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