TY - GEN
T1 - Real-Time Thermoacoustic Imaging and Thermometry during Focused Microwave Heating in Multilayer Breast Phantom
AU - Karunakaran, Chandra
AU - Saraswat, Srishti
AU - Tak, Jinpil
AU - Zhao, Hongbo
AU - Xin, Hao
AU - Witte, Russell S.
N1 - Funding Information:
This work is supported by DOD CDMRP Grant # W81XWH-16-1-0423 We acknowledge the UA Center for Gamma Ray Imaging (CGRI) for the use of their 3D printer.
Publisher Copyright:
© 2019 IEEE.
PY - 2019/10
Y1 - 2019/10
N2 - This study describes real-time thermoacoustic imaging (TAI) and thermometry (TAT) for feedback during thermal therapies. The system uses a linear ultrasound array and imaging system to noninvasively estimate temperature. The system was validated in gel phantoms, muscle and fat tissue samples. A mean error between 10 and 20% per degree was observed for estimating temperature. A TAT system using a single element ultrasound probe was also integrated with a focused microwave therapy (FMT) setup for generating local heating, leading to a mean error of 1.18±0.87 °C compared to thermocouples placed near the region of interest. The results support the long-term goal of developing a closed-loop platform for image-guided ablation therapy for breast cancer.
AB - This study describes real-time thermoacoustic imaging (TAI) and thermometry (TAT) for feedback during thermal therapies. The system uses a linear ultrasound array and imaging system to noninvasively estimate temperature. The system was validated in gel phantoms, muscle and fat tissue samples. A mean error between 10 and 20% per degree was observed for estimating temperature. A TAT system using a single element ultrasound probe was also integrated with a focused microwave therapy (FMT) setup for generating local heating, leading to a mean error of 1.18±0.87 °C compared to thermocouples placed near the region of interest. The results support the long-term goal of developing a closed-loop platform for image-guided ablation therapy for breast cancer.
KW - breast cancer
KW - focused microwave therapy
KW - hyperthermia
KW - radiofrequency ablation
UR - http://www.scopus.com/inward/record.url?scp=85077527392&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85077527392&partnerID=8YFLogxK
U2 - 10.1109/ULTSYM.2019.8925833
DO - 10.1109/ULTSYM.2019.8925833
M3 - Conference contribution
AN - SCOPUS:85077527392
T3 - IEEE International Ultrasonics Symposium, IUS
SP - 536
EP - 539
BT - 2019 IEEE International Ultrasonics Symposium, IUS 2019
PB - IEEE Computer Society
T2 - 2019 IEEE International Ultrasonics Symposium, IUS 2019
Y2 - 6 October 2019 through 9 October 2019
ER -