Real-time 3D thermoacoustic imaging and thermometry using a self-calibration technique

Ehab A. Tamimi, Hao Xin, Russell S. Witte

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Thermoacoustic (TA) imaging is a modality where pulsed microwaves are used to generate ultrasound waves in tissue, which are highly correlated with temperature. This study uses a self-calibration approach to improve the estimation of temperature using 3D real-time TA thermometry in porcine tissue during localized heating. The self-calibration method estimated temperatures at eight embedded thermocouple locations with a normalized root-mean-square error of 3.25 ± 2.08%. The results demonstrate that the method has the suitable accuracy and resolution to provide feedback control for breast cancer ablation therapy.

Original languageEnglish (US)
Pages (from-to)G255-G261
JournalApplied optics
Issue number22
StatePublished - Aug 1 2020

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Engineering (miscellaneous)
  • Electrical and Electronic Engineering


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