Reagentless detection of microorganisms by intrinsic fluorescence

Cory Estes, Andrew Duncan, Brad Wade, Christopher Lloyd, Walther Ellis, Linda Powers

Research output: Contribution to journalArticlepeer-review

54 Scopus citations


Quick and accurate detection of microbial contamination is accomplished by a unique combination of leading-edge technologies described in this and the accompanying paper. In this contribution, a hand-held prototype instrument is described which is capable of statistically sampling the environment for microbial contamination and determining cell viability. The technology is sensitive enough to detect very low levels (∼20 cells/cm2 or cm3) of microbes in seconds.

Original languageEnglish (US)
Pages (from-to)511-519
Number of pages9
JournalBiosensors and Bioelectronics
Issue number5-6
StatePublished - May 1 2003


  • Intrinsic fluorescence
  • Microbe sensor
  • Microbial contamination
  • Optical detection

ASJC Scopus subject areas

  • Biotechnology
  • Biophysics
  • Biomedical Engineering
  • Electrochemistry


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