Rational Design of a Highly Efficient Irreversible DNA Interstrand Cross-Linking Agent Based on the Pyrrolobenzodiazepine Ring System

D. Subhas Bose, Andrew S. Thompson, Jingshan Ching, John A. Hartley, Mark D. Berardini, Terence C. Jenkins, Stephen Neidle, Laurence H. Hurley, David E. Thurston

Research output: Contribution to journalArticlepeer-review

160 Scopus citations
Original languageEnglish (US)
Pages (from-to)4939-4941
Number of pages3
JournalJournal of the American Chemical Society
Issue number12
StatePublished - Jun 1 1992

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry
  • Biochemistry
  • Colloid and Surface Chemistry

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