Ratiometric and intensity-based zinc sensors built on rhodol and rhodamine platforms

Elisa Tomat; Stephen J. Lippard

doi:10.1021/ic101513a

Ratiometric and intensity-based zinc sensors built on rhodol and rhodamine platforms

Elisa Tomat, Stephen J. Lippard

Chemistry and Biochemistry

Research output: Contribution to journal › Article › peer-review

82 Scopus citations

Abstract

A xanthene-forming condensation reaction yields rhodol and rhodamine dyes carrying a zinc-binding ligand that includes the aniline-type nitrogen donor of the fluorophores. Upon zinc coordination in neutral aqueous solution, rhodol RF3 behaves as a ratiometric sensor, and rhodamine RA1 acts as a turn-off intensitybased indicator. Both fluorescent compounds bind the divalent zinc cation with micromolar affinity.

Original language	English (US)
Pages (from-to)	9113-9115
Number of pages	3
Journal	Inorganic Chemistry
Volume	49
Issue number	20
DOIs	https://doi.org/10.1021/ic101513a
State	Published - Oct 18 2010

ASJC Scopus subject areas

Physical and Theoretical Chemistry
Inorganic Chemistry

Access to Document

10.1021/ic101513a

Cite this

@article{3ac5e509d115454b997541e381d9740f,

title = "Ratiometric and intensity-based zinc sensors built on rhodol and rhodamine platforms",

abstract = "A xanthene-forming condensation reaction yields rhodol and rhodamine dyes carrying a zinc-binding ligand that includes the aniline-type nitrogen donor of the fluorophores. Upon zinc coordination in neutral aqueous solution, rhodol RF3 behaves as a ratiometric sensor, and rhodamine RA1 acts as a turn-off intensitybased indicator. Both fluorescent compounds bind the divalent zinc cation with micromolar affinity.",

author = "Elisa Tomat and Lippard, {Stephen J.}",

year = "2010",

month = oct,

day = "18",

doi = "10.1021/ic101513a",

language = "English (US)",

volume = "49",

pages = "9113--9115",

journal = "Inorganic Chemistry",

issn = "0020-1669",

publisher = "American Chemical Society",

number = "20",

}

TY - JOUR

T1 - Ratiometric and intensity-based zinc sensors built on rhodol and rhodamine platforms

AU - Tomat, Elisa

AU - Lippard, Stephen J.

PY - 2010/10/18

Y1 - 2010/10/18

N2 - A xanthene-forming condensation reaction yields rhodol and rhodamine dyes carrying a zinc-binding ligand that includes the aniline-type nitrogen donor of the fluorophores. Upon zinc coordination in neutral aqueous solution, rhodol RF3 behaves as a ratiometric sensor, and rhodamine RA1 acts as a turn-off intensitybased indicator. Both fluorescent compounds bind the divalent zinc cation with micromolar affinity.

AB - A xanthene-forming condensation reaction yields rhodol and rhodamine dyes carrying a zinc-binding ligand that includes the aniline-type nitrogen donor of the fluorophores. Upon zinc coordination in neutral aqueous solution, rhodol RF3 behaves as a ratiometric sensor, and rhodamine RA1 acts as a turn-off intensitybased indicator. Both fluorescent compounds bind the divalent zinc cation with micromolar affinity.

UR - http://www.scopus.com/inward/record.url?scp=78549269821&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78549269821&partnerID=8YFLogxK

U2 - 10.1021/ic101513a

DO - 10.1021/ic101513a

M3 - Article

C2 - 20860360

AN - SCOPUS:78549269821

VL - 49

SP - 9113

EP - 9115

JO - Inorganic Chemistry

JF - Inorganic Chemistry

SN - 0020-1669

IS - 20

ER -

Ratiometric and intensity-based zinc sensors built on rhodol and rhodamine platforms

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this