Randomized Controlled Trial of Qigong/Tai Chi Easy on Cancer-Related Fatigue in Breast Cancer Survivors

Linda K. Larkey, Denise J. Roe, Karen L. Weihs, Roger Jahnke, Ana Maria Lopez, Carol E. Rogers, Byeongsang Oh, Jose Guillen-Rodriguez

Research output: Contribution to journalArticlepeer-review

111 Scopus citations


Background: Many breast cancer survivors experience fatigue, mood, and sleep disturbances. Purpose: This study aims to compare a meditative movement practice, Qigong/Tai Chi Easy (QG/TCE) with sham Qigong (SQG), testing effects of meditation/breath aspects of QG/TCE on breast cancer survivors’ persistent fatigue and other symptoms. Methods: This double-blind, randomized controlled trial tested 12 weeks of QG/TCE versus SQG on fatigue, depression, and sleep among 87 postmenopausal, fatigued breast cancer survivors, stages 0–III, age 40–75. Results: Fatigue decreased significantly in the QG/TCE group compared to control at post-intervention (p = 0.005) and 3 months follow-up (p = 0.024), but not depression and sleep quality. Improvement occurred over time for both interventions in depression and sleep quality (all p < 0.05). Conclusions: QG/TCE showed significant improvement over time compared to SQG for fatigue, but not depression or sleep. Both QG/TCE and SQG showed improvement for two prevalent symptoms among breast cancer survivors, depression and sleep dysfunction.

Original languageEnglish (US)
Pages (from-to)165-176
Number of pages12
JournalAnnals of Behavioral Medicine
Issue number2
StatePublished - Apr 2015


  • Breast neoplasm
  • Fatigue
  • Qigong
  • Survivor symptoms
  • Tai Chi

ASJC Scopus subject areas

  • General Medicine


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