Abstract
A quinine-promoted, enantioselective Michael addition reaction of diphenyl phosphite with nitroalkenes has been developed. This methodology affords a facile access to enantiomerically enriched β-nitrophosphates, precursors for the preparation of synthetically and biologically useful β-aminophosphonates.
Original language | English (US) |
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Pages (from-to) | 1052-1056 |
Number of pages | 5 |
Journal | Advanced Synthesis and Catalysis |
Volume | 349 |
Issue number | 7 |
DOIs | |
State | Published - May 2007 |
Externally published | Yes |
Keywords
- Amino acids
- Asymmetric catalysis
- Michael addition
- Organic catalysis
ASJC Scopus subject areas
- Catalysis
- Organic Chemistry