Quindoline-derivatives display potent G-quadruplex-mediated antiviral activity against herpes simplex virus 1

Pharmacology, Toxicology and Pharmaceutical Science

• Human Alphaherpesvirus 1 100%
• Guanine Quadruplex 100%
• Antiviral Activity 100%
• Cytotoxicity 20%
• Infection 20%
• Antivirus Agent 20%
• Transcription Factors 20%
• Nucleic Acid 20%

Immunology and Microbiology

• Human Alphaherpesvirus 1 100%
• Antiviral Activity 100%
• Human Cell 40%
• Promoter Region 20%
• Virus Genome 20%
• Cytotoxicity 20%
• Transcription Factors 20%
• Viral Life Cycle 20%
• Biological Phenomena and Functions Concerning the Entire Organism 20%
• Nucleic Acid Structure 20%
• Viral Transcription 20%

Keyphrases

• Anti-herpes Simplex Virus 60%
• Best-in-class 20%
• Non-canonical nucleic Acid Structures 20%