Quantitative analysis of the electroencephalogram in the intracarotid amobarbital procedure

Geoffrey L. Ahern, David M. Labiner, Dinesh Talwar, Anne M. Herring, Martin E. Weinand

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Thirty-seven subjects underwent bilateral internal carotid artery injections of amobarbital before surgery for intractable epilepsy. The electroencephalograms (EEG) of these patients were continuously monitored during these 74 procedures and were later subjected to quantitative analysis. Analysis of inter-hemispheric coherence in the delta, theta, alpha, and beta 1 bands was performed. Prominent changes occurred in interhemispheric coherence, which showed a precipitous drop in the first 2 min after amobarbital injection, followed by a gradual return to near baseline levels. These results suggest that interhemispheric relationships are significantly disrupted by intracarotid amobarbital injection.

Original languageEnglish (US)
Pages (from-to)285-290
Number of pages6
JournalJournal of Clinical Neurophysiology
Issue number3
StatePublished - May 1995


  • Amobarbital
  • Coherence
  • Electroencephalography
  • Epilepsy
  • Intracarotid sodium amobarbital test
  • Quantitative electroencephalography
  • Wada test

ASJC Scopus subject areas

  • Physiology
  • Neurology
  • Clinical Neurology
  • Physiology (medical)


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