Pulvinar neuromodulation for seizure monitoring and network modulation in temporal plus epilepsy

Yash Shashank Vakilna, Ganne Chaitanya, Muhammad Ubaid Hafeez, Adeel Ilyas, Manojkumar Saranathan, Jay Gavvala, Nitin Tandon, Sandipan Pati

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Deep brain stimulation (DBS) is a promising treatment for drug-refractory epilepsies (DRE) when targeting the anterior nuclei of thalamus (ANT). However, targeting other thalamic nuclei, such as the pulvinar, shows therapeutic promise. Our pioneering case study presents the application of ambulatory seizure monitoring using spectral fingerprinting (12.15–17.15 Hz) recorded through Medtronic Percept DBS implanted bilaterally in the medial pulvinar thalami. This technology offers unprecedented opportunities for real-time monitoring of seizure burden and thalamocortical network modulation for effective seizure reduction in patients with bilateral mesial temporal and temporal plus epilepsies that are not suitable for resection.

Original languageEnglish (US)
Pages (from-to)1254-1259
Number of pages6
JournalAnnals of Clinical and Translational Neurology
Volume10
Issue number7
DOIs
StatePublished - Jul 2023
Externally publishedYes

ASJC Scopus subject areas

  • General Neuroscience
  • Clinical Neurology

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