Pulmonary nodule detection: What features attract attention?

The goal of the study was to determine if there are certain physical features of pulmonary nodules that attract visual attention and contribute to increased recognition and detection by observers. A series of posteroanterior chest images with solitary pulmonary nodules were searched by six radiologists as their eye-position was recorded. The signal-to-noise ratio, size, conspicuity, location, and calcification status were measured for each nodule. Dwell parameters were correlated with nodule features and related to detection rates. Only nodule size (F = 5.08, p = 0.0254) and conspicuity (F = 4.625, p = 0.0329) influenced total dwell time on nodules, with larger more conspicuous nodules receiving less visual attention than smaller less conspicuous nodules. All nodule features examined influenced overall detection performance (p < 0.05) even though most did not influence visual search and attention. Individual nodule features do not attract attention as measured by "first hit" fixation data, but certain features do tend to hold attention once the nodule has been fixated. The combination of all features influences whether or not it is detected.