Pulmonary abnormalities in patients intravenously receiving the methanol extraction residue (MER) of bacillus calmette‐guerin

Jorge R. Quesada; Herman I. Libshitz; Evan M. Hersh; Jordan U. Gutterman

doi:10.1002/1097-0142(19800315)45:6<1340::AID-CNCR2820450612>3.0.CO;2-7

Pulmonary abnormalities in patients intravenously receiving the methanol extraction residue (MER) of bacillus calmette‐guerin

Jorge R. Quesada, Herman I. Libshitz, Evan M. Hersh, Jordan U. Gutterman

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Eight of 64 patients receiving intravenous administration of methanol extraction residue (MER) of Bacillus Calmette‐Guerin (BCG), developed miliary‐type pulmonary parenchymal changes. The clinical and radiological characteristics are described. An increased incidence was noted in patients with a history of previous BCG exposure or with positive PPD skin reactivity. Spontaneous resolution was observed upon discontinuation of MER. These changes most likely represent a granulomatous inflammatory process, although no histological confirmation was obtained.

Original language	English (US)
Pages (from-to)	1340-1343
Number of pages	4
Journal	Cancer
Volume	45
Issue number	6
DOIs	https://doi.org/10.1002/1097-0142(19800315)45:6<1340::AID-CNCR2820450612>3.0.CO;2-7
State	Published - Mar 15 1980
Externally published	Yes

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1002/1097-0142(19800315)45:6<1340::AID-CNCR2820450612>3.0.CO;2-7

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title = "Pulmonary abnormalities in patients intravenously receiving the methanol extraction residue (MER) of bacillus calmette‐guerin",

abstract = "Eight of 64 patients receiving intravenous administration of methanol extraction residue (MER) of Bacillus Calmette‐Guerin (BCG), developed miliary‐type pulmonary parenchymal changes. The clinical and radiological characteristics are described. An increased incidence was noted in patients with a history of previous BCG exposure or with positive PPD skin reactivity. Spontaneous resolution was observed upon discontinuation of MER. These changes most likely represent a granulomatous inflammatory process, although no histological confirmation was obtained.",

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year = "1980",

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AU - Quesada, Jorge R.

AU - Libshitz, Herman I.

AU - Hersh, Evan M.

AU - Gutterman, Jordan U.

PY - 1980/3/15

Y1 - 1980/3/15

N2 - Eight of 64 patients receiving intravenous administration of methanol extraction residue (MER) of Bacillus Calmette‐Guerin (BCG), developed miliary‐type pulmonary parenchymal changes. The clinical and radiological characteristics are described. An increased incidence was noted in patients with a history of previous BCG exposure or with positive PPD skin reactivity. Spontaneous resolution was observed upon discontinuation of MER. These changes most likely represent a granulomatous inflammatory process, although no histological confirmation was obtained.

AB - Eight of 64 patients receiving intravenous administration of methanol extraction residue (MER) of Bacillus Calmette‐Guerin (BCG), developed miliary‐type pulmonary parenchymal changes. The clinical and radiological characteristics are described. An increased incidence was noted in patients with a history of previous BCG exposure or with positive PPD skin reactivity. Spontaneous resolution was observed upon discontinuation of MER. These changes most likely represent a granulomatous inflammatory process, although no histological confirmation was obtained.

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Pulmonary abnormalities in patients intravenously receiving the methanol extraction residue (MER) of bacillus calmette‐guerin

Abstract

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