Psychosocial variables affect the quality of life of men diagnosed with chronic prostatitis/chronic pelvic pain syndrome

J. Curtis Nickel, Dean A. Tripp, Shannon Chuai, Mark S. Litwin, Mary McNaughton-Collins, J. Richard Landis, Richard B. Alexander, Anthony J. Schaeffer, Michael P. O'Leary, Michel A. Pontari, Paige White, Christopher Mullins, Leroy Nyberg, John Kusek, Charles L. Bennett, Wade Bushman, Elizabeth A. Calhoun, Alisa Erika Koch, Robert B. Nadler, Mary HealyMarylin Dopona, Mary Buntin, Darlene Marko, James Duncan, Debra Rhodes, Judith Spolarich-Kroll, Alex Adler, Cindy Williams, Michael J. Barry, Dale Ardern, Janet Clark, Joseph Downey, Howard Ceri, Keith Jarvi, Lori L. Burrows, Michael R. Ruggieri, Linda Kish, Sharon Filer-Maerten, Dennis Cheng, George Drach, Cecilia Dobi, Bernadette Simpkiss, Scott I. Zeitlin, Yining Xie, Kellie Ma, Silvia Sanchez, Sathibalan Ponniah, Cindy S. Lowder, Kim Burton, Yvonne Underwood, Jackson E. Fowler, Rachael Tapley, Anne Dautenhahn, Dell Lumpkin, Daniel Shoskes, Kim Thomas, Eida Gomez, Nand S. Datta, Mary Ellen Raimo, Kawajalen Mervin, Craig V. Comiter, Pat Conrad, Kathleen J. Propert, John T. Farrar, Harold I. Feldman, Denise Cifelli, Stephen Durborow, Lori Fanelli, Xueyou Hu, Lee Randall, Jill S. Knauss, Randy Hildebrand, Gina Norwood, Marie Durborow, Christopher Helker, Robert M. Curley, Lori Kishel, Sarah Kang, Richard Farishian, Mary Harris, Mike Hennenfent, Clark Hickman, John Garst, Martin Stevens

Research output: Contribution to journalArticlepeer-review

73 Scopus citations


OBJECTIVE: To examine interactions between demographic, pain, urinary, psychological and environmental predictors of quality of life (QOL) in men with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). PATIENTS AND METHODS: In all, 253 men previously enrolled in the National Institutes of Health Chronic Prostatitis Cohort study in North American tertiary-care clinical centres (six in the USA and one in Canada) self-reported with validated instruments, including the QOL subscales of the Short Form-12 (physical, SF12-PCS; and mental, SF12-MCS), demographics, urinary symptoms, depression, current pain, pain coping, 'catastrophising' (catastrophic thinking about pain), pain control, social support and solicitous responses from a partner. Data were collected through a one-time survey. Covariates determined to be significant were entered into a multivariable regression model predicting SF12-PCS and SF12-MCS. RESULTS: Adjusting for covariates, regression models showed that poorer SF12-PCS scores were predicted by worse urinary function (P < 0.001) and increased use of pain-contingent resting as a coping strategy (P = 0.026). Further, poorer SF12-MCS scores were predicted by greater pain catastrophizing (P = 0.002) and lower perceptions of social support (P< 0.001). In separate follow-up analyses, helplessness was the significant catastrophizing subscale (P < 0.001), while support from family and friends were the significant social support subscales (P = 0.002 and <0.001). CONCLUSIONS: These data suggest that specific coping and environmental factors (i.e. catastrophizing, pain-contingent resting, social support) are significant in understanding how patients with CP/CPPS adjust. These data can be used to develop specific cognitive-behavioural programmes for men with CP/CPPS who are refractory to standard medical therapy.

Original languageEnglish (US)
Pages (from-to)59-64
Number of pages6
JournalBJU International
Issue number1
StatePublished - Jan 2008


  • Chronic pelvic pain syndrome
  • Chronic prostatitis
  • Psychosocial
  • Quality of life

ASJC Scopus subject areas

  • Urology


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