Abstract
The occurrence of pseudomalignant changes in biopsy specimens from two patients with ulcerative colitis and pseudopolyposis is described. One lesion was characterized by the proliferation of large ganglion cell-like cells, similar to those observed in proliferative faciitis. Ultrastructural and immunohistochemical findings supported a fibroblastic origin. Biopsy specimens of an inflammatory pseudopolyp from the second patient showed proliferation of oval to spindle cells that were initially interpreted as a possible neoplasm. The site of origin and reactive nature of this lesion became apparent on a subsequent polypectomy specimen. Attention is called to the occurrence of pseudosarcomatous changes in inflammatory pseudopolyps of the gastrointestinal tract that may lead to an erroneous diagnosis of malignancy.
Original language | English (US) |
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Pages (from-to) | 833-836 |
Number of pages | 4 |
Journal | Archives of Pathology and Laboratory Medicine |
Volume | 110 |
Issue number | 9 |
State | Published - 1986 |
Externally published | Yes |
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Medical Laboratory Technology