Abstract
Subcutaneous vaccination with recombinant antigen 2/PRA (rAg2/PRA) protected BALB/c mice against intranasal infection with Coccidioides immitis. Subcutaneously vaccinated C57BL/6 mice and intranasally vaccinated BALB/c mice were protected against larger numbers of infecting spores. Weight loss correlated with lethality, but histologic appearance did not. These studies support rAg2/PRA vaccination to prevent coccidioidomycosis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 3287-3289 |
| Number of pages | 3 |
| Journal | Infection and Immunity |
| Volume | 70 |
| Issue number | 6 |
| DOIs | |
| State | Published - 2002 |
ASJC Scopus subject areas
- Parasitology
- Microbiology
- Immunology
- Infectious Diseases