TY - JOUR
T1 - Prophylactic Human Papillomavirus Vaccination
T2 - A Breakthrough in Primary Cervical Cancer Prevention
AU - Garcia, Francisco A.R.
AU - Saslow, Debbie
PY - 2007/12
Y1 - 2007/12
N2 - Nearly all cervical cancers require human papillomavirus infection (HPV) for subsequent carcinogenesis. The identification of this obligate viral etiology, in addition to a vast knowledge about the HPV viral life cycle and resultant host response, has led to a vaccine approach to cervical cancer prevention. The use of prophylactic cancer vaccine as primary prevention holds the most promise for long-term cancer prevention but raises some important and as yet unanswered questions that are addressed in this article.
AB - Nearly all cervical cancers require human papillomavirus infection (HPV) for subsequent carcinogenesis. The identification of this obligate viral etiology, in addition to a vast knowledge about the HPV viral life cycle and resultant host response, has led to a vaccine approach to cervical cancer prevention. The use of prophylactic cancer vaccine as primary prevention holds the most promise for long-term cancer prevention but raises some important and as yet unanswered questions that are addressed in this article.
UR - http://www.scopus.com/inward/record.url?scp=36549029868&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=36549029868&partnerID=8YFLogxK
U2 - 10.1016/j.ogc.2007.09.007
DO - 10.1016/j.ogc.2007.09.007
M3 - Review article
C2 - 18061868
AN - SCOPUS:36549029868
SN - 0889-8545
VL - 34
SP - 761
EP - 781
JO - Obstetrics and Gynecology Clinics of North America
JF - Obstetrics and Gynecology Clinics of North America
IS - 4
ER -