Proof of Principle that Molecular Modeling Followed by a Biophysical Experiment Can Develop Small Molecules that Restore Function to the Cardiac Thin Filament in the Presence of Cardiomyopathic Mutations

Lukasz Szatkowski, Melissa L. Lynn, Teryn Holeman, Michael R. Williams, Anthony P. Baldo, Jil C. Tardiff, Steven D. Schwartz

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Engineering & Materials Science

Chemical Compounds