Prognostic factors in hairy cell leukemia. (Leukemic reticuloendotheliosis)

David J. Stewart, Terry L. Smith, Michael J. Keating, Kenneth B. McCredie, Evan M. Hersh, Jorge Quesada, Emil J. Freireich

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Prognostic factors were examined in 31 patients with hairy cell leukemia seen at M. D. Anderson Hospital. Long survival from presentation was significantly associated with ease of aspiration of iliac crest bone marrow, absence of major infection, hemoglobin > 10 g/dl, and absence of a prior history of pneumonia. Long survival from splenectomy was associated most closely with absence of a prediagnosis history of pneumonia, suggesting that a long‐standing host defense abnormality may exist that is not corrected by splenectomy. Generally, patients with sustained improvement in hematologic parameters postsplenectomy lived longest from splenectomy, although the results were not statistically significant. Cancer 53:1198‐1201, 1984.

Original languageEnglish (US)
Pages (from-to)1198-1201
Number of pages4
JournalCancer
Volume53
Issue number5
DOIs
StatePublished - Mar 1 1984

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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