Probing the structure of nanodiscs using surface-induced dissociation mass spectrometry

Sophie R. Harvey, Zachary L. Vanaernum, Marius M. Kostelic, Michael T. Marty, Vicki H. Wysocki

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

In the study of membrane proteins and antimicrobial peptides, nanodiscs have emerged as a valuable membrane mimetic to solubilze these molecules in a lipid bilayer. We present the structural characterization of nanodiscs using native mass spectrometry and surface-induced dissociation, which are powerful tools in structural biology. This journal is

Original languageEnglish (US)
Pages (from-to)15651-15654
Number of pages4
JournalChemical Communications
Volume56
Issue number100
DOIs
StatePublished - Dec 28 2020

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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