Probing structure and function in planar supported protein films

S. Scott Saavedra; Paul L. Edmiston; John E. Lee; Laurie L. Wood; Darren R. Dunphy; Rebecca T. Robertson; Elizabeth A. Gabbard; Sergio B. Mendes

doi:10.1117/12.372910

Probing structure and function in planar supported protein films

S. Scott Saavedra, Paul L. Edmiston, John E. Lee, Laurie L. Wood, Darren R. Dunphy, Rebecca T. Robertson, Elizabeth A. Gabbard, Sergio B. Mendes

Research output: Contribution to journal › Conference article › peer-review

Abstract

The development of molecular devices based on immobilized protein films is currently a very active area of research worldwide. Detailed structural and functional characterization of these films is a prerequisite to the rational development of deposition methods that produce bioactive structures, but is a technically difficult challenge. Two recent thrusts in our work have been investigation of methods designed to create macroscopically ordered arrays of protein molecules, and development of new optical techniques to characterize the ensemble properties of these arrays.

Original language	English (US)
Pages (from-to)	146-150
Number of pages	5
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	3858
DOIs	https://doi.org/10.1117/12.372910
State	Published - 1999
Externally published	Yes
Event	Proceedings of the 1999 Advanced Materials and Optical Systems for Chemical and Biological Detection - Boston, MA, USA Duration: Sep 21 1999 → Sep 22 1999

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

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10.1117/12.372910

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title = "Probing structure and function in planar supported protein films",

abstract = "The development of molecular devices based on immobilized protein films is currently a very active area of research worldwide. Detailed structural and functional characterization of these films is a prerequisite to the rational development of deposition methods that produce bioactive structures, but is a technically difficult challenge. Two recent thrusts in our work have been investigation of methods designed to create macroscopically ordered arrays of protein molecules, and development of new optical techniques to characterize the ensemble properties of these arrays.",

author = "Saavedra, {S. Scott} and Edmiston, {Paul L.} and Lee, {John E.} and Wood, {Laurie L.} and Dunphy, {Darren R.} and Robertson, {Rebecca T.} and Gabbard, {Elizabeth A.} and Mendes, {Sergio B.}",

year = "1999",

doi = "10.1117/12.372910",

language = "English (US)",

volume = "3858",

pages = "146--150",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

issn = "0277-786X",

publisher = "SPIE",

note = "Proceedings of the 1999 Advanced Materials and Optical Systems for Chemical and Biological Detection ; Conference date: 21-09-1999 Through 22-09-1999",

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TY - JOUR

T1 - Probing structure and function in planar supported protein films

AU - Saavedra, S. Scott

AU - Edmiston, Paul L.

AU - Lee, John E.

AU - Wood, Laurie L.

AU - Dunphy, Darren R.

AU - Robertson, Rebecca T.

AU - Gabbard, Elizabeth A.

AU - Mendes, Sergio B.

PY - 1999

Y1 - 1999

N2 - The development of molecular devices based on immobilized protein films is currently a very active area of research worldwide. Detailed structural and functional characterization of these films is a prerequisite to the rational development of deposition methods that produce bioactive structures, but is a technically difficult challenge. Two recent thrusts in our work have been investigation of methods designed to create macroscopically ordered arrays of protein molecules, and development of new optical techniques to characterize the ensemble properties of these arrays.

AB - The development of molecular devices based on immobilized protein films is currently a very active area of research worldwide. Detailed structural and functional characterization of these films is a prerequisite to the rational development of deposition methods that produce bioactive structures, but is a technically difficult challenge. Two recent thrusts in our work have been investigation of methods designed to create macroscopically ordered arrays of protein molecules, and development of new optical techniques to characterize the ensemble properties of these arrays.

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U2 - 10.1117/12.372910

DO - 10.1117/12.372910

M3 - Conference article

AN - SCOPUS:0033348846

SN - 0277-786X

VL - 3858

SP - 146

EP - 150

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

T2 - Proceedings of the 1999 Advanced Materials and Optical Systems for Chemical and Biological Detection

Y2 - 21 September 1999 through 22 September 1999

ER -

Probing structure and function in planar supported protein films

Abstract

ASJC Scopus subject areas

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